I run entirely off of avalon macros, which does, in fact, require me to press enter. XD
Basically, I've done it like this- single digits, like 1,2,3,4, ect. are potions. double digits are door locks- entrances and exits generally right next to each other. 11 use to be my wild card macro because I use to change it all the time, but now it's be come a stable one as well. So now, and number in the teens is a wild card that I change up depending on what I'm doing at the time, although one of them has some how become something that I probably won't change in the future because it's come in handy, haha.
Besides that, I have maybe 5 aliases for stone work and that's about it.
My setup isn't very extensive. :B